March 2023

2022–2023 Board of Directors
Published in issue: March 2023
S1-S3

2023 Program Committee
Published in issue: March 2023
S4

INVITED SPEAKERS

THE ROLE OF ADIPOSE-CARTILAGE CROSSTALK IN OSTEOARTHRITIS
• K.H. Collins,
• E.V. Ely,
• H.D. Welhaven,
• ...
• B. Zhang,
• R.K. June,
• F. Guilak
Published in issue: March 2023
S5-S6

2023 OARSI ORAL ABSTRACTS

Increased Joint Loading 1 Month After Platelet-Rich Plasma Treatment Of Knee OA Is Associated With Improved Clinical Outcomes 2 Years Later
• J. He,
• J.C. Erhart-Hledik,
• C.R. Chu
Published in issue: March 2023
S7-S8

Safety And Preliminary Efficacy Of Pcrx201, An Intra-Articular Gene Therapy For Knee Osteoarthritis: A Phase 1, Open-Label, Single Ascending Dose Study
• S. Cohen,
• A. Kivitz,
• L. Klassen,
• ...
• D. Parenti,
• M. DiGiorgi,
• R. Winston
Published in issue: March 2023
S8-S9

Combination Of Computational Methods With A Drug Repurposing Strategy Identifies A Compound Targeting Chondrocyte Hypertrophy
• J. Veldman,
• M.N. Ferrao Blanco,
• N.K. Kops,
• ...
• J. van Rooij,
• E. Farrell,
• G.J. van Osch
Published in issue: March 2023
S9

Automatic Identification Of Pain-Associated Imaging Abnormalities From Knee Mri Imaging By Deep Generative Networks
• P.-H. Lian,
• T. Chuang,
• Y.-H. Yen,
• G. Chang
Published in issue: March 2023
S9-S10

Radiomics Features Of Infrapatellar Fat Pad Are Associated With Symptomatic And Radiographic Post-Traumatic Osteoarthritis At 10+ Years After Acl Reconstruction
• S. Khan,
• R. Lartey,
• N. Obuchowski,
• ...
• C.C. Kaeding,
• K.P. Spindler,
• X. Li
Published in issue: March 2023
S10-S12

Comparative Efficacy Of Interventions For Reducing Psychological Symptoms In Patients With Osteoarthritis: A Network Meta-Analysis
• Y. Li,
• Y. Mai,
• X. Fang,
• X. Shi,
• C. Ding,
• Z. Zhu
Published in issue: March 2023
S12
Anterior Knee Pain Is Associated With 2-Year Compartment Specific Patellofemoral Cartilage Worsening: The Most Study
• C. Lanois,
• N. Collins,
• T. Neogi,
• ...
• J. Torner,
• C. Lewis,
• J. Stefanik
Published in issue: March 2023
S13

Pharmacological Modulation Of Krüppel-Like Factor 4 Reduces The Severity Of Experimental Osteoarthritis Via Tissue Protection And Regeneration
• M. Kawata,
• M. Olmer,
• K.A. Johnson,
• M.K. Lotz
Published in issue: March 2023
S13-S14

Subchondral Bone Remodeling Differs Between Anterior Cruciate Ligament Transection, Non-Invasive Anterior Cruciate Ligament Rupture, And Medial Meniscus Transection Models Of Post-Traumatic Osteoarthritis
• M. Bowe,
• T. AJAYI,
• A. OBERDORFER,
• B. SHARMA,
• K.D. ALLEN
Published in issue: March 2023
S14-S15
Transcriptomic profiling of osteoarthritis patient synovial macrophages reveals a tolerized phenotype compounded by a weak corticosteroid response.
• C. Wang,
• R. De Francesco,
• L.A. Lamers,
• ...
• P.L. van Lent,
• C. Logie,
• M.H. van den Bosch
Published in issue: March 2023
S15
The Regulation Of Ngf, Semaphorins And Glutamate Signalling By Mechanical Loading And Inflammation In A 3-Dimensional Model Of Human Stem Cell Derived Osteocytes
• R. Jones,
• D. Mason,
• S. Gilbert
Published in issue: March 2023
S15-S16
Collaborative Model Of Care Between Orthopaedics And Allied Healthcare Professionals (Connact) For Knee Osteoarthritis: 12-Months Follow-Up Of An Effectiveness-Implementation Hybrid Trial
• B. Tan,
• M. Pereira,
• S.-Y. Yang,
• ...
• S. Skou,
• J. Thumboo,
• J. Car
Published in issue: March 2023
S16-S17

Exercise Therapy Compared To Usual Care In People With Early-Stage Knee Oa: An Individual Patient Data Meta-Analysis From The Oa Trial Bank
• M. van Middelkoop,
• D. Schiphof,
• M. Hattle,
• ...
• M.V. Hurley,
• M. Holden,
• S.M. Bierma-Zeinstra
Published in issue: March 2023
S17

Physical Activity And The Risk Of Knee And Hip Osteoarthritis: A Mendelian Randomization Study
• H. He,
• Y. Zhang,
• D.K. White,
• ...
• J. Wei,
• C. Zeng,
• G. Lei
Published in issue: March 2023
S18-S19
Prevalence Of Early Knee Osteoarthritis Illness Using Knee Injury And Osteoarthritis Outcome Score Criteria Following Anterior Cruciate Ligament Reconstruction In New Zealand
• S. Ward,
• D. O'Brien,
• R. Meiring,
• H. Love,
• M. Harkey
Published in issue: March 2023
S19
Co-Creating Injury Prevention Education And Training For Youth Handball Players Targeting End-Users At The Individual, Team And Organizational Levels
• E. Ageberg,
• S. Bunke,
• J. Linnéll,
• K. Moesch
Published in issue: March 2023
S19-S20

Impact Of Weight Loss And Local Subcutaneous Fat On Knee Joint Synovitis Over 4 Years: Data From The Osteoarthritis Initiative
• M.T. Loeffler,
• P. Giesler,
• J.A. Lynch,
• ...
• M. Nevitt,
• C. McCulloch,
• T.M. Link
Published in issue: March 2023
S20-S22

Nod2 Attenuates Osteoarthritis Via Reprogramming Inflammatory Response Of Synovial Macrophages
• C. Li,
• S. Lin,
• Z. Ouyang,
• S. Li,
• T. Liu,
• Y. Ding
Published in issue: March 2023
S22

Antibody mediated IL12 pathway modulation has a disease modifiying effect on post-traumatic osteoarthritis in mice.
• P. Haubruck,
• C. Blaker,
• C. Hill,
• ...
• E. Clarke,
• C. Shu,
• C. Little
Published in issue: March 2023
S23-S24

Cartilage-Specific SIRT6 Loss Increases Surgery-Induced And Age-Associated Oa In Mice
• J.A. Collins,
• C. Kim,
• A. Coleman,
• ...
• M. Peffers,
• T. Freeman,
• R. Loeser
Published in issue: March 2023
S24

Excessive Mechanical Stress Enhances Mechanical Stress Sensitivity Of Cartilage Through The Mechanosensitive Ion Channel Piezo2
• S. Kawabata,
• T. Kojima,
• K. Takeshita,
• ...
• C. Takasu,
• N. Kanemura,
• K. Murata
Published in issue: March 2023
S24-S25

Cartilage Specific Transforming Growth Factor Beta Receptor II Deletion Drives Medial Collateral Ligament Calcification In Spontaneous Mouse OA
• J. St Amant,
• J. Michaud,
• L. De Guzman,
• ...
• J. Trujillo Torres,
• A. Pozzi,
• A.L. Clark
Published in issue: March 2023
S25-S26
Anti-Inflammatory Polymers As Potential Therapeutics In Knee Osteoarthritis
• C. Aulin,
• T. Melander-Bowden,
• H. Erlandsson-Harris,
• T. Engstrand
Published in issue: March 2023
S26

3d Printed Cartilage Mimetic Composite Postpones Onset Of Skeletal Deformities In A Rabbit Model Of Growth Plate Injury
• K.M. Fischenich,
• F. Rodriguez-Fontan,
• S. Thomas,
• ...
• V.L. Ferguson,
• S.J. Bryant,
• K.A. Payne
Published in issue: March 2023
S26-S27

Biomimetic And Bioactive Hydrogels With Tethered Growth Factors For Cartilage Regeneration
• L. Stefani,
• S. Schoonraad,
• S. Bryant
Published in issue: March 2023
S27-S28
Priming Of Hoffa-Derived MSC With IL1Β In Vertical Wheel Bioreactor Culture Yields Extracellular Vesicles Hindering Chondrocyte Recovery Compared To Unstimulated MSCS
• A. Otahal,
• K. Kramer,
• L. Moser,
• Z. Lacza,
• S. Nehrer,
• A. De Luna
Published in issue: March 2023
S28
Adjunctive Therapies In Addition To Land-Based Exercise Therapy For Osteoarthritis Of The Hip Or Knee: A Cochrane Review
• H.P. French,
• J. Abbott,
• R. Galvin
Published in issue: March 2023
S29
Optimising Management Of Knee Osteoarthritis In Primary Care (Partner): A Cluster Randomised Controlled Trial
• J.L. Bowden,
• D.J. Hunter,
• R.S. Hinman,
• ...
• S.M. Silva,
• G.Z. Heller,
• K.L. Bennell
Published in issue: March 2023
S29-S30

Effectiveness Of An 11-Week Exercise Intervention For Patients With Hip Or Knee Osteoarthritis On Health-Related Quality Of Life, Self-Efficacy And Joint Replacement
• I. Krauss,
• I. Roesel,
• P. Martus,
• G. Mueller
Published in issue: March 2023
S30

The Effects Of A Disruptive Digital Technology Intervention Following Total Knee Replacement: Results From The Pathway Randomised Controlled Trial
• V. Duong,
• S. Dennis,
• A. Harris,
• ...
• V. Venkatesha,
• M. Ferreira,
• D.J. Hunter
Published in issue: March 2023
S30-S31
Only patients’ expectations are prognostic for dissatisfaction with performing work-related knee-straining activities after total knee arthroplasty. A multicenter cohort study
• Y. van Zaanen,
• T. Siertsema,
• T.M. Pahlplatz,
• ...
• D.H. Das,
• V.A. Scholtes,
• P.F. Kuijer
Published in issue: March 2023
S32

Raav-Mediated Fgf-2 And TGF-β Overexpression Via Alginate Hydrogel Delivery Stimulates The Reparative Abilities Of Human Meniscal Lesions In Situ
• J.K. Venkatesan,
• P. Orth,
• H. Madry,
• M. Cucchiarini
Published in issue: March 2023
S32-S33

Generalized Osteoarthritis And Subsequent Changes In Thigh Muscle Quality: Observational Longitudinal Analysis Using Osteoarthritis Initiative
• K. Moradi,
• B. Mohajer,
• F.W. Roemer,
• A. Guermazi,
• S. Demehri
Published in issue: March 2023
S33-S34
Multi-Lipid Synergy In Cartilage Lubrication: Redundancy Or Evolution?
• J. Klein,
• Y. Cao
Published in issue: March 2023
S34-S35

The Biological Response Of Anterior Cruciate Ligamentocytes Following Treatment With Synovial Fluid Extracellular Vesicles
• D. Cookson,
• E. Comerford,
• J. Anderson,
• M. Peffers,
• Y. Ashraf Kharaz
Published in issue: March 2023
S35

Pgc-1α As A Mechanistic Driver Of Exercise-Induced Regulation Of Intermuscular Adipose: In Silico Approach Of GSEA-Guided Network Propagation
• H. Iijima,
• Y. Matsui
Published in issue: March 2023
S35-S36

The association between statistical shape variations of the hip and the development of radiographic hip osteoarthritis within 8 years of follow-up: data from 17,738 hips in the world coach consortium.
• M.M. van Buuren,
• F.D. Boel,
• N.S. Riedstra,
• ...
• J. Tang,
• H. Weinans,
• R. Agricola
Published in issue: March 2023
S36-S38

What Do Radiographic Minimum And Fixed-Position Joint Space Width Measure? A Comparison Of Radiographic And MRI Measures From The Osteoarthritis INITIATIVE
• A. Brett,
• M. Bowes,
• P.G. Conaghan
Published in issue: March 2023
S38-S39

Patterns Of Oa Development On Mri In High-Risk Women With Overweight And Obesity And The Role Of Bone Marrow Lesions
• J. Runhaar,
• E. Macri,
• E. Oei,
• S. Bierma-Zeinstra
Published in issue: March 2023
S39

Three-Dimensional Ultrasound For Quantitation Of Synovial Tissue Volume In Knee Osteoarthritis
• R.S. Dima,
• T. Birmingham,
• C. du Toit,
• J. Polus,
• A. Fenster,
• C. Appleton
Published in issue: March 2023
S39-S40

Histological Validation Of The Textural Features From Quantitative MRI For Determination Of Cartilage Degeneration
• V. Juras,
• S. Toegel,
• B. Hager,
• ...
• W.J. Weninger,
• R. Windhager,
• S. Trattnig
Published in issue: March 2023
S40-S42

Deep Immunophenotyping Of Osteoarthritis Patients Demonstrates Baseline Alterations In Monocyte Populations In OA, Dendritic Cell Subpopulations Among Radiographic Progressors, And TH17 Cells Among Pain Progressors.
• E. Holmlund,
• L. Schlupp,
• G. Dyson,
• M. Barrett,
• M. Jeffries
Published in issue: March 2023
S42-S43

Hypertension Exacerbates Joint Pathology In A Surgical Model Of Osteoarthritis In A Sex-Dependent Manner
• T. Yeater,
• J.L. Griffith,
• C.J. Cruz,
• F.M. Patterson,
• J.L. Aldrich,
• K.D. Allen
Published in issue: March 2023
S43-S44
The Peculiarities Of Intestinal Microbiome In Patients With Osteoarthritis
• O. Gubska,
• A. Kuzminets,
• O. Koliada,
• V. Moseyko
Published in issue: March 2023
S44

The Relationship Of Osteoarthritis And Hypertension On Pain And Depression
• Y. Yip,
• C. Wen
Published in issue: March 2023
S44-S45

Association Between Metabolic Syndrome And Knee Pain Over 10-13 Years In Middle-Aged Adults
• B. Eathakkattu Antony,
• A. Singh,
• B. Fraser,
• ...
• L. Blizzard,
• G. Jones,
• C. Ding
Published in issue: March 2023
S45-S46

Radiographic Changes Following Surgical And Non-Surgical Treatment For Degenerative Meniscal Tear
• J.N. Katz,
• J.E. Collins,
• M.H. Jones,
• ...
• B.A. Levy,
• C.L. Cox,
• Y. Chang
Published in issue: March 2023
S46