April 2022

2021-2022 Board of Directors
Published in issue: April 2022
S1-S3

2022 Program Committee
Published in issue: April 2022
S4

INVITED SPEAKERS

Tissue Engineering to Treat Cartilage Defects and Model Osteoarthritis
• Gerjo J.V.M. van Osch
Published in issue: April 2022
S5
On the Role of Artificial Intelligence in Solving the Osteoarthritis Puzzle
• Valentina Pedoia
Published in issue: April 2022
S5
COVID-19 & OA: From a Pharmacological Perspective
• Karin Magnusson
Published in issue: April 2022
S5
The Science of Placebo, to Understand the Importance of Placebo Effects in OA:
• David Felson
Published in issue: April 2022
S5-S6
Non-Coding RNA Signature in Painful Knee OA:
• Lars Arendt-Nielsen
Published in issue: April 2022
S6
Rehabilitation & Outcomes
• Melanie Holden
Published in issue: April 2022
S6
OA Biology
• Seungwoo Han
Published in issue: April 2022
S6

2022 OARSI ORAL ABSTRACTS

APPLICATION OF MAGNETIC PARTICLE TECHNOLOGY TO ASSESS NANOPARTICLE LOCALIZATION TO CARTILAGE
• T.O. Ajayi,
• S. Liu,
• C. Rosen,
• C. Rinaldi,
• B. Sharma
Published in issue: April 2022
S7

KNEE OSTEOARTHRITIS-ASSOCIATED THIGH MUSCLE MRI CHANGES AND THEIR CONTRIBUTION TO CLINICAL OUTCOME:USE OF ARTIFICIAL INTELLIGENCE ON OSTEOARTHRITIS INITIATIVEDATA
• B. Mohajer,
• M. Dolatshahi,
• K. Moradi,
• ...
• F.W. Roemer,
• A. Guermazi,
• S. Demehri
Published in issue: April 2022
S8-S10

CLUSTERING AND DIMENSIONAL REDUCTION FOR VISUALIZING KNEE OSTEOARTHRITIS PHENOTYPES: DATA FROM THE OAI
• Z. Huang,
• W. Guo,
• J. Martin
Published in issue: April 2022
S10-S11

PINCER MORPHOLOGY IS NOT ASSOCIATED WITH DEVELOPMENT OF HIP OSTEOARTHRITIS WITHIN 10 YEARS; A NATIONWIDE PROSPECTIVE COHORT STUDY (CHECK)
• N. Riedstra,
• J. Herfkens,
• J. Tang,
• ...
• J. Runhaar,
• M.M. van Buuren,
• R. Agricola
Published in issue: April 2022
S11

INVESTIGATING THE MECHANO-IMMUNE RESPONSE OF CARTILAGE AND THE SYNOVIAL MEMBRANE USING A JOINT-ON-CHIP APPROACH
• C. Paggi,
• N. Araújo-Gomes,
• A. Zuchowska,
• ...
• E. van Hengel,
• S. Le Gac,
• M. Karperien
Published in issue: April 2022
S12

OSTEOARTHRITIS-RISK MUTATION IN PERICELLULAR MATRIX COL6A3 FIBRILS ALTERS BIOLOGIC RESPONSE OF CHONDROCYTES TO HYPER-PHYSIOLOGIC MECHANICAL LOADING CONDITIONS
• N.G. Bloks,
• Z. Harissa,
• A. Dicks,
• ...
• F. Guilak,
• Y.F. Ramos,
• I. Meulenbelt
Published in issue: April 2022
S12-S13
PREVALENCE AND FACTORS ASSOCIATED WITH INADEQUATE PAIN RELIEF IN PEOPLE WITH HIP OR KNEE OSTEOARTHRITIS: A CROSS-SECTIONAL POPULATION BASED STUDY
• D. Costa,
• E. Cruz,
• C. Nunes da Silva,
• ...
• J. Branco,
• C. Nunes,
• A. Rodrigues
Published in issue: April 2022
S13-S14

BABS ON A MISSION: AN EXPERIMENTAL STUDY ON THE EFFECTS OF MESSAGE FRAMING AND EXEMPLIFICATION ON TREATMENT INTENTIONS OF OSTEOARTHRITIS PATIENTS
• J.M. Oomen,
• C.H. van den Ende,
• H.J. Schers,
• S. Koëter,
• W.J. Assendelft,
• H.H. Das
Published in issue: April 2022
S14
CAN CONTINUOUS KNEE PAIN OUTCOME MEASURES BE HARMONISED?
• V. Georgopoulos,
• T.A. Perry,
• S.L. Smith,
• ...
• F.E. Watt,
• D.A. Walsh
• for the STEP-UP OA Consortium
Published in issue: April 2022
S15-S17

DEVELOPMENT OF AN INTERVENTION TO IMPROVE IDENTIFICATION AND MANAGEMENT OF CONCOMITANT KNEE OSTEOARTHRITIS IN PERSONS WITH TYPE 2 DIABETES AND PHYSICAL INACTIVITY
• L.K. King,
• N.M. Ivers,
• E.J. Waugh,
• ...
• J. Stretton,
• L. Lipscombe,
• G.A. Hawker
Published in issue: April 2022
S17

IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION IMBALANCED OSTEOARTHRITIS ASSOCIATED FIBRONECTIN SPLICE VARIANTS
• M. van Hoolwerff,
• M. Tuerlings,
• I.J. Wijnen,
• ...
• Y.F. Ramos,
• R. Coutinho de Almeida,
• I. Meulenbelt
Published in issue: April 2022
S17-S18

RELIABILITY OF WEARABLE SENSORS FOR ASSESSING GAIT AND CHAIR STAND FUNCTION AT HOME IN PEOPLE WITH KNEE OSTEOARTHRITIS
• M.J. Rose,
• T. Neogi,
• B. Friscia,
• ...
• C. Demanuele,
• P. Wacnick,
• D. Kumar
Published in issue: April 2022
S18-S19
UNDERLOADING, NOT OVERLOADING, OF THE PATELLOFEMORAL JOINT INCREASES THE RISK OF EARLY OSTEOARTHRITIS AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
• A. Culvenor,
• A. Schache,
• P. Sritharan,
• ...
• H. Morris,
• T. Whitehead,
• K. Crossley
Published in issue: April 2022
S19-S20

POTENTIAL SURROGATE OUTCOMES FOR INCIDENT KNEE OSTEOARTHRITIS AMONG OVERWEIGHT AND OBESE WOMEN
• J. Runhaar,
• M. van Middelkoop,
• E. Oei,
• S. Bierma-Zeinstra
Published in issue: April 2022
S20

EARLY MENISCAL SURGERY OR EXERCISE THERAPY AND EDUCATION WITH THE OPTION OF LATER SURGERY IN YOUNG ADULTS: A RANDOMIZED CONTROLLED TRIAL
• S.T. Skou,
• P. Hölmich,
• M. Lind,
• ...
• C. Jensen,
• M. Garval,
• J.B. Thorlund
Published in issue: April 2022
S20-S21

SPONTANEOUS HEALING OF THE RUPTURED ANTERIOR CRUCIATE LIGAMENT: OBSERVATIONS FROM THE KANON TRIAL
• S. Filbay,
• F. Roemer,
• S. Lohmander,
• ...
• E.M. Roos,
• R. Frobell,
• M. Englund
Published in issue: April 2022
S21-S22

PREDICTION MODELS TO ESTIMATE FUTURE INDIVIDUAL RISK OF OSTEOARTHRITIS IN THE GENERAL POPULATION: A SYSTEMATIC REVIEW
• T. Appleyard,
• D. Antcliff,
• M. Thomas,
• G. Peat
Published in issue: April 2022
S22

SYNOVITIS DETECTED BY ULTRASONOGRAPHY PREDICT THE RISK OF DEVELOPING KNEE OSTEOARTHRITIS IN EARLY KNEE OSTEOARTHRITIS FROM THE IWAKI COHORT STUDY
• K. Ishibashi,
• E. Sasaki,
• D. Chiba,
• ...
• Y. Yamamoto,
• E. Tsuda,
• Y. Ishibashi
Published in issue: April 2022
S23-S24

OSMOLARITY-INDUCED ALTERED INTRACELLULAR MOLECULAR CROWDING DRIVES OSTEOARTHRITIS PATHOLOGY
• K. Govindaraj,
• M. Meteling,
• M. Becker,
• J. Post,
• J. Leijten
Published in issue: April 2022
S24-S25
INHIBITION OF LOX MEDIATED EXTRACELLULAR MATRIX STIFFENING PREVENTS WNT3A INDUCED CHONDROCYTE DIFFERENTIATION VIA THE YAP/ TAZ PATHWAY
• A. Held,
• M. Bollmann,
• U. Hansen,
• ...
• H. Clausen-Schaumann,
• C.H. Lohmann,
• J. Bertrand
Published in issue: April 2022
S25

BCP CRYSTALS IN OSTEOARTHRITIS; UNRAVELLING THE CHANGING CHONDROCYTE SECRETOME
• R. Stassen,
• G. van den Akker,
• D. Surtel,
• ...
• M. Peffers,
• L. van Rhijn,
• T. Welting
Published in issue: April 2022
S26

NOTCH SIGNALING CONTRIBUTES TO THE DEVELOPMENT OF KNEE HYPERALGESIA IN MICE
• L. Wang,
• S. Ishihara,
• J. Li,
• R.E. Miller,
• A.-M. Malfait
Published in issue: April 2022
S26-S27
SINGLE NUCLEI RNA-SEQUENCING OF PORCINE ARTICULAR CARTILAGE UNCOVERS THE CHONDROCYTES CLUSTERS THAT CHANGE IN RESPONSE TO MECHANICAL INJURY
• L. Zhu,
• L. Koneva,
• M. Attar,
• J. Webber,
• S. Sansom,
• T.L. Vincent
Published in issue: April 2022
S27
NADPH OXIDASE 4 DEFICIENCY ATTENUATES EXPERIMENTAL OSTEOARTHRITIS IN MICE
• F. Renaudin,
• K.-S. Oudina,
• M. Subilia,
• M. Gerbaix,
• T. Laumonier,
• D. Hannouche
Published in issue: April 2022
S27-S28

CHARACTERIZING THE COMBINED EFFECT OF PHYSICAL ACTIVITY MEASURES ON STRUCTURAL PROGRESSION OF OA: THE MULTICENTER OSTEOARTHRITIS STUDY
• K.E. Costello,
• A. Guermazi,
• F.W. Roemer,
• ...
• M.C. Nevitt,
• D.T. Felson,
• S. Jafarzadeh
Published in issue: April 2022
S28

IMPROVED WOMAC PHYSICAL FUNCTION IS ASSOCIATED WITH SLOWED PATHOLOGICAL BONE SHAPE CHANGE AFTER TPX-100: TOWARDS A SURROGATE MARKER FOR VIRTUAL KNEE REPLACEMENT?
• D. McGuire,
• M. Bowes,
• A. Brett,
• ...
• M. Miller,
• D. Rosen,
• Y. Kumagai
Published in issue: April 2022
S28-S29

ASSOCIATEION BETWEEN LEVOTHYROXINE USE AND LONGITUDINAL THIGH MUSCLES QUALITY AND RISK OF KNEE OSTEOARTHRITIS INCIDENCE: OSTEOARTHRITIS INITIATIVE DATA
• B. Mohajer,
• K. Moradi,
• M. Dolatshahi,
• A. Guermazi,
• F. Roemer,
• S. Demehri
Published in issue: April 2022
S29-S31

DEVELOPMENT AND VALIDATION OF PREDICTION MODELS FOR THE RISK OF TOTAL KNEE REPLACEMENT USING DATA FROM MULTI-CENTER COHORT STUDIES
• Q. Liu,
• H. Chu,
• M.P. LaValley,
• ...
• S. Zhan,
• Y. Zhang,
• J. Lin
Published in issue: April 2022
S31-S32

A COMPARISON OF ULTRASOUND-DETECTED PATHOLOGIES IN PERSONS WITH AND WITHOUT KNEE OSTEOARTHRITIS AND THE ASSOCIATIONS WITH PAIN
• C. Dekkerhus,
• A. Mathiessen,
• B. Slatkowsky-Christensen,
• H.B. Hammer,
• I.K. Haugen
Published in issue: April 2022
S32-S33

EFFECTIVENESS OF EXERCISE- AND PHYSICAL ACTIVITY INTERVENTIONS ON FATIGUE IN PEOPLE WITH OSTEOARTHRITIS: A SYSTEMATIC REVIEW WITH META-ANALYSIS.
• C. Labie,
• N. Runge,
• O. Mairesse,
• ...
• A. Arribas,
• J. Nijs,
• L. De Baets
Published in issue: April 2022
S33

IS HIP JOINT LOADING DURING WALKING ASSOCIATED WITH CARTILAGE DEFECT SEVERITY AND CAM MORPHOLOGY IN FOOTBALL PLAYERS WITH HIP AND GROIN PAIN?
• K. Crossley,
• Y.-C. Lin,
• A. Schache,
• ...
• R. Souza,
• T. Link,
• M. Pandy
Published in issue: April 2022
S33-S34
MUSCLE FORCES DURING WEIGHTBEARING EXERCISES IN MEDIAL KNEE OSTEOARTHRITIS AND VARUS MALALIGNMENT: A CROSS-SECTIONAL STUDY
• S.C. Starkey,
• L.E. Diamond,
• R.S. Hinman,
• D.J. Saxby,
• G. Knox,
• M. Hall
Published in issue: April 2022
S34-S35

PREDICTING CHANGE IN KNEE CARTILAGE FROM INTERACTIONS OF CUMULATIVE LOADING WITH CARTILAGE TURNOVER BIOMARKERS: DATA FROM THE OSTEOARTHRITIS INITIATIVE
• N.K. Ivanochko,
• A.A. Gatti,
• P.W. Stratford,
• M.R. Maly
Published in issue: April 2022
S35-S36

ANGIOGENESIS AND ENDOTHELIAL DYSFUNCTION: SYNOVIAL VASCULAR PATHOLOGY IS ASSOCIATED WITH SURROGATE MEASURES OF KNEE LOAD DURING WALKING
• M.M. Carter,
• T.B. Birmingham,
• H.T. Philpott,
• J.R. Giffin,
• B.A. Lanting,
• C.T. Appleton
Published in issue: April 2022
S36-S37

MACHINE LEARNING FOR ASSOCIATION OF WEARABLE-SENSOR DERIVED GAIT MEASURES WITH WORSENING KNEE PAIN OVER 2-YEARS: THE MULTICENTER OSTEOARTHRITIS STUDY
• K.L. Bacon,
• D.T. Felson,
• S.R. Jafarzadeh,
• ...
• C.E. Lewis,
• M.C. Nevitt,
• D. Kumar
Published in issue: April 2022
S37

ASSOCIATION OF CHANGES IN GAIT BIOMECHANICS AFTER HIGH TIBIAL OSTEOTOMY WITH SUBSEQUENT TOTAL KNEE REPLACEMENT
• C.A. Primeau,
• T.B. Birmingham,
• K.M. Leitch,
• ...
• R.B. Litchfield,
• P.J. Fowler,
• R. Giffin
Published in issue: April 2022
S37-S38
β2-ADRENOCEPTOR DEFICIENCY LEADS TO INCREASED SUBCHONDRAL BONE REMODELING AND CALCIFIED CARTILAGE THICKNESS IN A MURINE KNEE OSTEOARTHRITIS MODEL
• G. Roesch,
• D. Muschter,
• S. Taheri,
• ...
• S. Graessel,
• R. Straub,
• Z. Jenei-Lanzl
Published in issue: April 2022
S38-S39

CD38 DEFICIENCY PROTECTS MICE FROM AGE-RELATED SPONTANEOUS OA DEVELOPMENT
• R. Liu-Bryan,
• P. Alabarse,
• H. Qin
Published in issue: April 2022
S39-S40
DEFINING THE HIERARCHY OF FIBROBLASTS AND THEIR STEM CELLS IN THE ADULT SYNOVIAL JOINT AT SINGLE CELL RESOLUTION
• F.L. Collins,
• A.J. Roelofs,
• K. Kania,
• E. Campbell,
• E.S. Collie-duguid,
• C. De Bari
Published in issue: April 2022
S40
INHIBITION OF HISTONE DEMETHYLASES AS AN APPROACH TO RESTORE DEFICIENT DOT1L ACTIVITY IN OSTEOARTHRITIS
• R. Assi,
• C. Cherifi,
• F. Cornelis,
• R. Lories,
• S. Monteagudo
Published in issue: April 2022
S40-S41

GENDER BIAS IN OSTEOARTHRITIS: THE SUSHI CONNECTION
• M.Y. Ansari,
• K. Novak,
• T.M. Haqqi
Published in issue: April 2022
S41