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From weight loss to weight gain: utilizing the full spectrum of weight management for behavioral intervention

  • S.L. Mihalko
    Correspondence
    Address correspondence and reprint requests to: S.L. Mihalko, Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.
    Affiliations
    Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA
    Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA
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  • S.P. Messier
    Affiliations
    J.B. Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA
    Department of Rheumatology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC, USA
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Published:December 02, 2022DOI:https://doi.org/10.1016/j.joca.2022.11.011
      Reducing the prevalence of overweight and obesity has been a primary focus in the management and prevention of chronic disease, including diabetes, cancer, and knee osteoarthritis (OA)
      • Chooi Y.C.
      • Ding C.
      • Magkos F.
      The epidemiology of obesity.
      ,
      • Jastreboff A.M.
      • Kotz C.M.
      • Kahan S.
      • Kelly A.S.
      • Heymsfield S.B.
      Obesity as a disease: the obesity society 2018 position statement.
      . Specific to knee OA, obesity can accelerate disease progression and contribute to disability. Consequently, a 5–10% weight loss combined with exercise is among the most prescribed and effective non-surgical treatments for knee OA, recommended as part of best practice by several international guidelines and resulting in important clinical and mechanistic outcomes, including reductions in pain and improvements in function and health-related quality of life.
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