Among the many risk factors for osteoarthritis (OA), obesity and metabolic syndrome
(MetS) are increasing in importance with societal escalation in sedentary lifestyles
and consumption of unhealthy Western diets
1
,2
. There is a bidirectional relationship between obesity/MetS and OA
3
, while the increased OA risk associated with obesity/MetS can also be transmitted
intergenerationally through epigenetic modification
4
.To read this article in full you will need to make a payment
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Article info
Publication history
Published online: December 02, 2022
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© 2022 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
