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Evidence suggests that intraarticular corticosteroids are effective (short term) and safe (long term)

Published:October 20, 2022DOI:https://doi.org/10.1016/j.joca.2022.10.010
      In a meta-analysis recently published in Osteoarthritis and Cartilage, Donovan et al.
      • Donovan R.
      • Edwards T.
      • Judge A.
      • et al.
      Effects of recurrent intra-articular corticosteroid injections for osteoarthritis at three months and beyond.
      stated that ‘recurrent intraarticular corticosteroids (IACS) often provide inferior (or non-superior) longer-term symptom relief compared with other injectables’. However, after carrying out meta-analyses of treatments for osteoarthritis (OA) or reviewing comprehensive ones, many guidelines committees have recommended IACS, at least conditionally, for the treatment of OA. What is the evidence supporting the efficacy and safety of IACS, and how can we make sense of these conflicting findings/recommendations?

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