Adult bone marrow stromal cell-based tissue-engineered aggrecan exhibits ultrastructure and nanomechanical properties superior to native cartilage

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Volume 18, Issue 11 , Pages 1477-1486, November 2010

H.-Y. Lee
- Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States
P.W. Kopesky
- Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States
A. Plaas
- Department of Biochemistry, Rush University Medical Center, Chicago, IL, United States
J. Sandy
- Department of Biochemistry, Rush University Medical Center, Chicago, IL, United States
J. Kisiday
- Equine Orthopaedic Research Center, Colorado State University, Fort Collins, CO, United States
D. Frisbie
- Equine Orthopaedic Research Center, Colorado State University, Fort Collins, CO, United States
A.J. Grodzinsky
- Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States
- Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States
- Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States
C. Ortiz
- Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States
- Address correspondence and reprint requests to: C. Ortiz, Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States. Tel: 1-617-452-3084.