Osteoarthritis and Cartilage
Volume 18, Issue 10 , Pages 1355-1357 , October 2010

Cathepsin K inhibition reduces CTXII levels and joint pain in the guinea pig model of spontaneous osteoarthritis

  • J.J. McDougall

      Affiliations

    • Department of Physiology & Pharmacology, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada
    • Corresponding Author InformationAddress correspondence and reprint requests to: Jason J. McDougall, Department of Physiology & Pharmacology, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada. Tel: 1-403-2204507; Fax:1-403-2103949.
    • ,
  • N. Schuelert

      Affiliations

    • Department of Physiology & Pharmacology, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada
    • ,
  • J. Bowyer

      Affiliations

    • Respiratory & Inflammation Research Area, AstraZeneca, Charnwood, Loughborough, Leicestershire LE11 5RH, UK

Received 18 May 2010 ,Accepted 30 July 2010.

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PII: S1063-4584(10)00252-9

doi: 10.1016/j.joca.2010.07.014

Osteoarthritis and Cartilage
Volume 18, Issue 10 , Pages 1355-1357 , October 2010

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