Osteoarthritis and Cartilage
Volume 18, Issue 11 , Pages 1454-1457 , November 2010

Association of single-nucleotide polymorphisms in HLA class II/III region with knee osteoarthritis

  • D. Shi

      Affiliations

    • The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing 210008, Jiangsu, China
    • Australia-China Joint Laboratory for Bone and Joint Disease, Model Animal Research Center (MARC), Nanjing University, Nanjing 210093, China
    • These authors contributed equally to this work.
    • ,
  • Q. Zheng

      Affiliations

    • Division of Orthopaedic Surgery, Department of Surgery, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China
    • These authors contributed equally to this work.
    • ,
  • D. Chen

      Affiliations

    • The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing 210008, Jiangsu, China
    • ,
  • L. Zhu

      Affiliations

    • The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing 210008, Jiangsu, China
    • ,
  • A. Qin

      Affiliations

    • Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Cawley WA 6009, Australia
    • Department of Orthopaedics, Ninth People’s Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, PR China
    • ,
  • J. Fan

      Affiliations

    • The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing 210008, Jiangsu, China
    • ,
  • J. Liao

      Affiliations

    • Division of Orthopaedic Surgery, Department of Surgery, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China
    • ,
  • Z. Xu

      Affiliations

    • The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing 210008, Jiangsu, China
    • ,
  • Z. Lin

      Affiliations

    • Division of Orthopaedic Surgery, Department of Surgery, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, PR China
    • ,
  • P. Norman

      Affiliations

    • School of Surgery at Fremental Hospital, The University of Western Australia, Cawley WA 6009, Australia
    • ,
  • J. Xu

      Affiliations

    • Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Cawley WA 6009, Australia
    • ,
  • T. Nakamura

      Affiliations

    • Laboratory for Mathematics, National Defense Medical College, Saitama 359-8513, Japan
    • ,
  • K. Dai

      Affiliations

    • Department of Orthopaedics, Ninth People’s Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, PR China
    • ,
  • M. Zheng

      Affiliations

    • Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Cawley WA 6009, Australia
    • Corresponding Author InformationAddress correspondence and reprint requests to: Minghao Zheng, Orthopaedic Surgery (Centre for Orthopaedic Research), The University of Western Australia (M508), Crawley WA 6009, Australia. Tel: 61-93464050; Fax: 61-93463210.
    • ,
  • Q. Jiang

      Affiliations

    • The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing 210008, Jiangsu, China
    • Australia-China Joint Laboratory for Bone and Joint Disease, Model Animal Research Center (MARC), Nanjing University, Nanjing 210093, China
    • Corresponding Author InformationAddress correspondence and reprint requests to: Qing Jiang, The Center of Diagnosis and Treatment for Joint Disease, Drum Tower Hospital Affiliated to Medical School of Nanjing University, Zhongshan Road 321, Nanjing 210008, Jiangsu, China. Tel: 86-25-83107008; Fax: 86-25-83317016.

Received 8 April 2010 ,Accepted 20 July 2010.

References 

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  2. Hirsch R, Lethbridge-Cejku M, Hanson R, Scott WW, Reichle R, Plato CC, et al. Familial aggregation of osteoarthritis: data from the Baltimore Longitudinal Study on Aging. Arthritis Rheum. 1998;41:1227–1232
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  8. Jiang Q, Shi D, Yi L, Ikegawa S, Wang Y, Nakamura T, et al. Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese. J Hum Genet. 2006;51(12):1068–1072
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  15. Nakamura T, Shi D, Tzetis M, Rodriguez-Lopez J, Miyamoto Y, Tsezou A, et al. Meta-analysis of association between the ASPN D-repeat and osteoarthritis. Hum Mol Genet. 2007;16(14):1676–1681

PII: S1063-4584(10)00245-1

doi: 10.1016/j.joca.2010.07.009

Osteoarthritis and Cartilage
Volume 18, Issue 11 , Pages 1454-1457 , November 2010

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