Osteoarthritis and Cartilage
Volume 18, Issue 9 , Pages 1174-1182 , September 2010

Surface grafting of biocompatible phospholipid polymer MPC provides wear resistance of tibial polyethylene insert in artificial knee joints

  • T. Moro

      Affiliations

    • Department of Science for Joint Reconstruction, The University of Tokyo, Hongo 7-3-1, Bunkyo, Tokyo 113-0033, Japan
  • ,
  • Y. Takatori

      Affiliations

    • Department of Science for Joint Reconstruction, The University of Tokyo, Hongo 7-3-1, Bunkyo, Tokyo 113-0033, Japan
  • ,
  • M. Kyomoto

      Affiliations

    • Department of Science for Joint Reconstruction, The University of Tokyo, Hongo 7-3-1, Bunkyo, Tokyo 113-0033, Japan
  • ,
  • K. Ishihara

      Affiliations

    • Department of Materials Engineering, The University of Tokyo, Hongo 7-3-1, Bunkyo, Tokyo 113-0033, Japan
  • ,
  • K. Saiga

      Affiliations

    • Department of Science for Joint Reconstruction, The University of Tokyo, Hongo 7-3-1, Bunkyo, Tokyo 113-0033, Japan
  • ,
  • K. Nakamura

      Affiliations

    • Department of Sensory & Motor System Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo, Tokyo 113-0033, Japan
  • ,
  • H. Kawaguchi

      Affiliations

    • Department of Sensory & Motor System Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo, Tokyo 113-0033, Japan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Hiroshi Kawaguchi, Sensory & Motor System Medicine, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo, Tokyo 113-8655, Japan. Tel: 81-3-3815-5411x30473; Fax: 81-3-3818-4082.

Received 20 January 2010 ,Accepted 29 May 2010.

References 

  1. Kim S. Changes in surgical loads and economic burden of hip and knee replacements in the US: 1997–2004. Arthritis Rheum. 2008;59:481–488
  2. Kurtz SM, Mowat F, Ong K, Chan N, Lau E, Halpern M. Prevalence of primary and revision total hip and knee arthroplasty in the United States from 1990 through 2002. J Bone Joint Surg Am. 2005;87:1487–1497
  3. Sharkey PF, Hozack WJ, Rothman RH, Shastri S, Jacoby SM. Insall Award paper. Why are total knee arthroplasties failing today?. Clin Orthop Relat Res. 2002;404:7–13
  4. Jacobs JJ, Roebuck KA, Archibeck M, Hallab NJ, Glant TT. Osteolysis: basic science. Clin Orthop Relat Res. 2001;393:71–77
  5. Naudie DD, Ammeen DJ, Engh GA, Rorabeck CH. Wear and osteolysis around total knee arthroplasty. J Am Acad Orthop Surg. 2007;15:53–64
  6. Glant TT, Jacobs JJ, Molnar G, Shanbhag AS, Valyon M, Galante JO. Bone resorption activity of particulate-stimulated macrophages. J Bone Miner Res. 1993;8:1071–1079
  7. Akagi M, Asano T, Clarke IC, Niiyama N, Kyomoto M, Nakamura T, et al. Wear and toughness of crosslinked polyethylene for total knee replacements: a study using a simulator and small-punch testing. J Orthop Res. 2006;24:2021–2027
  8. Chiesa R, Tanzi MC, Alfonsi S, Paracchini L, Moscatelli M, Cigada A. Enhanced wear performance of highly crosslinked UHMWPE for artificial joints. J Biomed Mater Res. 2000;50:381–387
  9. Fisher J, McEwen HM, Tipper JL, Galvin AL, Ingram J, Kamali A, et al. Wear, debris, and biologic activity of cross-linked polyethylene in the knee: benefits and potential concerns. Clin Orthop Relat Res. 2004;428:114–119
  10. Muratoglu OK, Bragdon CR, Jasty M, O’Connor DO, Von Knoch RS, Harris WH. Knee-simulator testing of conventional and cross-linked polyethylene tibial inserts. J Arthroplasty. 2004;19:887–897
  11. Muratoglu OK, Rubash HE, Bragdon CR, Burroughs BR, Huang A, Harris WH. Simulated normal gait wear testing of a highly cross-linked polyethylene tibial insert. J Arthroplasty. 2007;22:435–444
  12. Tsukamoto R, Williams PA, Clarke IC, Pezzotti G, Shoji H, Akagi M, et al. Y-TZP zirconia run against highly crosslinked UHMWPE tibial inserts: knee simulator wear and phase-transformation studies. J Biomed Mater Res B Appl Biomater. 2008;86:145–153
  13. Tsukamoto R, Williams PA, Shoji H, Hirakawa K, Yamamoto K, Tsukamoto M, et al. Wear in molded tibial inserts: knee simulator study of H1900 and GUR1050 polyethylenes. J Biomed Mater Res B Appl Biomater. 2008;85:314–319
  14. D’Antonio JA, Manley MT, Capello WN, Bierbaum BE, Ramakrishnan R, Naughton M, et al. Five-year experience with Crossfire highly cross-linked polyethylene. Clin Orthop Relat Res. 2005;441:143–150
  15. Dorr LD, Wan Z, Shahrdar C, Sirianni L, Boutary M, Yun A. Clinical performance of a Durasul highly cross-linked polyethylene acetabular liner for total hip arthroplasty at five years. J Bone Joint Surg Am. 2005;87:1816–1821
  16. Dowson D, Jin ZM. Micro-elastohydrodynamic lubrication of synovial joints. Eng Med. 1986;15:63–65
  17. Hills BA. Boundary lubrication in vivo. Proc Inst Mech Eng [H]. 2000;214:83–94
  18. Kirk TB, Wilson AS, Stachowiak GW. The morphology and composition of the superficial zone of mammalian articular cartilage. J Orthop Rheumatol. 1993;6:21–28
  19. Ishihara K, Ueda T, Nakabayashi N. Preparation of phospholipid polymers and their properties as polymer hydrogel membrane. Polym J. 1990;22:355–360
  20. Ishihara K, Shinozuka T, Hanazaki Y, Iwasaki Y, Nakabayashi N. Improvement of blood compatibility on cellulose hemodialysis membrane: IV. Phospholipid polymer bonded to the membrane surface. J Biomater Sci Polym Ed. 1999;10:271–282
  21. Yoneyama T, Sugihara K, Ishihara K, Iwasaki Y, Nakabayashi N. The vascular prosthesis without pseudointima prepared by antithrombogenic phospholipid polymer. Biomaterials. 2002;23:1455–1459
  22. Kyomoto M, Moro T, Konno T, Takadama H, Kawaguchi H, Takatori Y, et al. Effects of photo-induced graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on physical properties of cross-linked polyethylene in artificial hip joints. J Mater Sci Mater Med. 2007;18:1809–1815
  23. Kyomoto M, Moro T, Konno T, Takadama H, Yamawaki N, Kawaguchi H, et al. Enhanced wear resistance of modified cross-linked polyethylene by grafting with poly(2-methacryloyloxyethyl phosphorylcholine). J Biomed Mater Res A. 2007;82:10–17
  24. Moro T, Takatori Y, Ishihara K, Konno T, Takigawa Y, Matsushita T, et al. Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis. Nat Mater. 2004;3:829–836
  25. Moro T, Takatori Y, Ishihara K, Nakamura K, Kawaguchi H. 2006 Frank Stinchfield Award: grafting of biocompatible polymer for longevity of artificial hip joints. Clin Orthop Relat Res. 2006;453:58–63
  26. Kyomoto M, Moro T, Miyaji F, Konno T, Hashimoto M, Kawaguchi H, et al. Enhanced wear resistance of orthopaedic bearing due to the cross-linking of poly(MPC) graft chains induced by gamma-ray irradiation. J Biomed Mater Res B Appl Biomater. 2008;84:320–327
  27. Kurtz SM, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am. 2007;89:780–785
  28. Moro T, Kawaguchi H, Ishihara K, Kyomoto M, Karita T, Ito H, et al. Wear resistance of artificial hip joints with poly(2-methacryloyloxyethyl phosphorylcholine) grafted polyethylene: comparisons with the effect of polyethylene cross-linking and ceramic femoral heads. Biomaterials. 2009;30:2995–3001
  29. Kumar P, Oka M, Ikeuchi K, Shimizu K, Yamamuro T, Okumura H, et al. Low wear rate of UHMWPE against zirconia ceramic (Y-PSZ) in comparison to alumina ceramic and SUS 316L alloy. J Biomed Mater Res. 1991;25:813–828
  30. Schwenke T, Kaddick C, Schneider E, Wimmer MA. Fluid composition impacts standardized testing protocols in ultrahigh molecular weight polyethylene knee wear testing. Proc Inst Mech Eng H. 2005;219:457–464
  31. Tipper JL, Ingham E, Hailey JL, Besong AA, Fisher J, Wroblewski BM, et al. Quantitative analysis of polyethylene wear debris, wear rate and head damage in retrieved Charnley hip prostheses. J Mater Sci Mater Med. 2000;11:117–124
  32. Campbell P, Doorn P, Dorey F, Amstutz HC. Wear and morphology of ultra-high molecular weight polyethylene wear particles from total hip replacements. Proc Inst Mech Eng H. 1996;210:167–174
  33. Dean DD, Schwartz Z, Liu Y, Blanchard CR, Agrawal CM, Mabrey JD, et al. The effect of ultra-high molecular weight polyethylene wear debris on MG63 osteosarcoma cells in vitro. J Bone Joint Surg Am. 1999;81:452–461
  34. Kurtz SM, Foulds JR, Jewett CW, Srivastav S, Edidin AA. Validation of a small punch testing technique to characterize the mechanical behaviour of ultra-high-molecular-weight polyethylene. Biomaterials. 1997;18:1659–1663
  35. Beaule PE, Campbell PA, Walker PS, Schmalzried TP, Dorey FJ, Blunn GW, et al. Polyethylene wear characteristics in vivo and in a knee stimulator. J Biomed Mater Res. 2002;60:411–419
  36. Tipper JL, Galvin AL, Williams S, McEwen HM, Stone MH, Ingham E, et al. Isolation and characterization of UHMWPE wear particles down to ten nanometers in size from in vitro hip and knee joint simulators. J Biomed Mater Res A. 2006;78:473–480
  37. Ishihara K, Nomura H, Mihara T, Kurita K, Iwasaki Y, Nakabayashi N. Why do phospholipid polymers reduce protein adsorption?. J Biomed Mater Res. 1998;39:323–330
  38. Edidin AA, Pruitt L, Jewett CW, Crane DJ, Roberts D, Kurtz SM. Plasticity-induced damage layer is a precursor to wear in radiation-cross-linked UHMWPE acetabular components for total hip replacement. Ultra-high-molecular-weight polyethylene. J Arthroplasty. 1999;14:616–627
  39. Kurtz SM, Pruitt LA, Jewett CW, Foulds JR, Edidin AA. Radiation and chemical crosslinking promote strain hardening behavior and molecular alignment in ultra high molecular weight polyethylene during multi-axial loading conditions. Biomaterials. 1999;20:1449–1462
  40. Green TR, Fisher J, Stone M, Wroblewski BM, Ingham E. Polyethylene particles of a ‘critical size’ are necessary for the induction of cytokines by macrophages in vitro. Biomaterials. 1998;19:2297–2302
  41. Galvin AL, Tipper JL, Ingham E, Fisher J. Nanometre size wear debris generated from crosslinked and non-crosslinked ultra high molecular weight polyethylene in artificial joints. Wear. 2005;259:977–983
  42. Ingram JH, Stone M, Fisher J, Ingham E. The influence of molecular weight, crosslinking and counterface roughness on TNF-alpha production by macrophages in response to ultra high molecular weight polyethylene particles. Biomaterials. 2004;25:3511–3522
  43. Ahn NU, Nallamshetty L, Ahn UM, Buchowski JM, Rose PS, Lemma MA, et al. Early failure associated with the use of Hylamer-M spacers in three primary AMK total knee arthroplasties. J Arthroplasty. 2001;16:136–139
  44. Wright TM, Rimnac CM, Faris PM, Bansal M. Analysis of surface damage in retrieved carbon fiber-reinforced and plain polyethylene tibial components from posterior stabilized total knee replacements. J Bone Joint Surg Am. 1988;70:1312–1319

PII: S1063-4584(10)00211-6

doi: 10.1016/j.joca.2010.05.019

Osteoarthritis and Cartilage
Volume 18, Issue 9 , Pages 1174-1182 , September 2010