Osteoarthritis and Cartilage
Volume 18, Issue 9 , Pages 1133-1143 , September 2010

Changes of human menisci in osteoarthritic knee joints

  • Y. Katsuragawa

      Affiliations

    • Department of Orthopaedic Surgery, National Center for Global Health and Medicine, Tokyo, Japan
    • Department of Pathology, National Center for Global Health and Medicine, Tokyo, Japan
    • ,
  • K. Saitoh

      Affiliations

    • Department of Orthopaedic Surgery, National Center for Global Health and Medicine, Tokyo, Japan
    • Department of Pathology, National Center for Global Health and Medicine, Tokyo, Japan
    • Deceased.
    • ,
  • N. Tanaka

      Affiliations

    • Clinical Research Center, National Hospital Organization, Sagamihara Hospital, Kanagawa, Japan
    • ,
  • M. Wake

      Affiliations

    • Clinical Research Center, National Hospital Organization, Sagamihara Hospital, Kanagawa, Japan
    • ,
  • Y. Ikeda

      Affiliations

    • Clinical Research Center, National Hospital Organization, Sagamihara Hospital, Kanagawa, Japan
    • ,
  • H. Furukawa

      Affiliations

    • Clinical Research Center, National Hospital Organization, Sagamihara Hospital, Kanagawa, Japan
    • ,
  • S. Tohma

      Affiliations

    • Clinical Research Center, National Hospital Organization, Sagamihara Hospital, Kanagawa, Japan
    • ,
  • M. Sawabe

      Affiliations

    • Department of Pathology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan
    • ,
  • M. Ishiyama

      Affiliations

    • Department of Clinical Laboratory, Kanagawa Rehabilitation Hospital, Kanagawa, Japan
    • ,
  • S. Yagishita

      Affiliations

    • Department of Clinical Laboratory, Kanagawa Rehabilitation Hospital, Kanagawa, Japan
    • ,
  • R. Suzuki

      Affiliations

    • Clinical Research Center, National Hospital Organization, Sagamihara Hospital, Kanagawa, Japan
    • ,
  • H. Mitomi

      Affiliations

    • Department of Pathology, Jyuntendo University School of Medicine, Tokyo, Japan
    • ,
  • N. Fukui

      Affiliations

    • Clinical Research Center, National Hospital Organization, Sagamihara Hospital, Kanagawa, Japan
    • Corresponding Author InformationAddress correspondence and reprint requests to: Naoshi Fukui, Clinical Research Center, National Hospital Organization, Sagamihara Hospital, Sakuradai 18-1, Sagamihara, Minami-ku, Kanagawa 252-0315, Japan. Tel/Fax: 81-42-742-8311.

Received 16 November 2009 ,Accepted 29 May 2010.

References 

  1. Guccione AA, Felson DT, Anderson JJ, Anthony JM, Zhang Y, Wilson PW, et al. The effects of specific medical conditions on the functional limitations of elders in the Framingham Study. Am J Public Health. 1994;84:351–358
  2. Noble J, Hamblen DL. The pathology of the degenerate meniscus lesion. J Bone Joint Surg Br. 1975;57:180–186
  3. Cheung HS. Distribution of type I, II, III and V in the pepsin solubilized collagens in bovine menisci. Connect Tissue Res. 1987;16:343–356
  4. Eyre DR, Wu JJ. Collagen of fibrocartilage: a distinctive molecular phenotype in bovine meniscus. FEBS Lett. 1983;158:265–270
  5. Hellio Le Graverand MP, Vignon E, Otterness IG, Hart DA. Early changes in lapine menisci during osteoarthritis development: Part I: cellular and matrix alterations. Osteoarthritis Cartilage. 2001;9:56–64
  6. Hellio Le Graverand MP, Vignon E, Otterness IG, Hart DA. Early changes in lapine menisci during osteoarthritis development: Part II: molecular alterations. Osteoarthritis Cartilage. 2001;9:65–72
  7. Herwig J, Egner E, Buddecke E. Chemical changes of human knee joint menisci in various stages of degeneration. Ann Rheum Dis. 1984;43:635–640
  8. Kambic HE, McDevitt CA. Spatial organization of types I and II collagen in the canine meniscus. J Orthop Res. 2005;23:142–149
  9. Nakano T, Dodd CM, Scott PG. Glycosaminoglycans and proteoglycans from different zones of the porcine knee meniscus. J Orthop Res. 1997;15:213–220
  10. Scott PG, Nakano T, Dodd CM. Isolation and characterization of small proteoglycans from different zones of the porcine knee meniscus. Biochim Biophys Acta. 1997;1336:254–262
  11. Valiyaveettil M, Mort JS, McDevitt CA. The concentration, gene expression, and spatial distribution of aggrecan in canine articular cartilage, meniscus, and anterior and posterior cruciate ligaments: a new molecular distinction between hyaline cartilage and fibrocartilage in the knee joint. Connect Tissue Res. 2005;46:83–91
  12. Wojtys EM, Chan DB. Meniscus structure and function. Instr Course Lect. 2005;54:323–330
  13. Gale DR, Chaisson CE, Totterman SM, Schwartz RK, Gale ME, Felson D. Meniscal subluxation: association with osteoarthritis and joint space narrowing. Osteoarthritis Cartilage. 1999;7:526–532
  14. Berthiaume MJ, Raynauld JP, Martel-Pelletier J, Labonte F, Beaudoin G, Bloch DA, et al. Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging. Ann Rheum Dis. 2005;64:556–563
  15. Hunter DJ, Zhang YQ, Niu JB, Tu X, Amin S, Clancy M, et al. The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritis. Arthritis Rheum. 2006;54:795–801
  16. Petersen W, Tillmann B. Collagenous fibril texture of the human knee joint menisci. Anat Embryol (Berl). 1998;197:317–324
  17. Kavanagh E, Ashhurst DE. Distribution of biglycan and decorin in collateral and cruciate ligaments and menisci of the rabbit knee joint. J Histochem Cytochem. 2001;49:877–885
  18. Spindler KP, Miller RR, Andrish JT, McDevitt CA. Comparison of collagen synthesis in the peripheral and central region of the canine meniscus. Clin Orthop Relat Res. 1994;256–263
  19. Upton ML, Hennerbichler A, Fermor B, Guilak F, Weinberg JB, Setton LA. Biaxial strain effects on cells from the inner and outer regions of the meniscus. Connect Tissue Res. 2006;47:207–214
  20. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum. 1986;29:1039–1049
  21. Fukui N, Miyamoto Y, Nakajima M, Ikeda Y, Hikita A, Furukawa H, et al. Zonal gene expression of chondrocytes in osteoarthritic cartilage. Arthritis Rheum. 2008;58:3843–3853
  22. Tashiro T, Hiraoka H, Ikeda Y, Ohnuki T, Suzuki R, Ochi T, et al. Effect of GDF-5 on ligament healing. J Orthop Res. 2006;24:71–79
  23. Joshi MD, Suh JK, Marui T, Woo SL. Interspecies variation of compressive biomechanical properties of the meniscus. J Biomed Mater Res. 1995;29:823–828
  24. Mow VC, Kuei SC, Lai WM, Armstrong CG. Biphasic creep and stress relaxation of articular cartilage in compression? Theory and experiments. J Biomech Eng. 1980;102:73–84
  25. Ingman AM, Ghosh P, Taylor TK. Variation of collagenous and non-collagenous proteins of human knee joint menisci with age and degeneration. Gerontologia. 1974;20:212–223
  26. Ghosh P, Ingman AM, Taylor TK. Variations in collagen, non-collagenous proteins, and hexosamine in menisci derived from osteoarthritic and rheumatoid arthritic knee joints. J Rheumatol. 1975;2:100–107
  27. Bullough PG, Munuera L, Murphy J, Weinstein AM. The strength of the menisci of the knee as it relates to their fine structure. J Bone Joint Surg Br. 1970;52:564–567
  28. Liu SH, Yang RS, al-Shaikh R, Lane JM. Collagen in tendon, ligament, and bone healing. A current review. Clin Orthop Relat Res. 1995;265–278
  29. Bullard KM, Longaker MT, Lorenz HP. Fetal wound healing: current biology. World J Surg. 2003;27:54–61
  30. Pangborn CA, Athanasiou KA. Growth factors and fibrochondrocytes in scaffolds. J Orthop Res. 2005;23:1184–1190
  31. Tumia NS, Johnstone AJ. Regional regenerative potential of meniscal cartilage exposed to recombinant insulin-like growth factor-I in vitro. J Bone Joint Surg Br. 2004;86:1077–1081
  32. Imler SM, Doshi AN, Levenston ME. Combined effects of growth factors and static mechanical compression on meniscus explant biosynthesis. Osteoarthritis Cartilage. 2004;12:736–744
  33. McNulty AL, Guilak F. Integrative repair of the meniscus: lessons from in vitro studies. Biorheology. 2008;45:487–500
  34. Gunther M, Haubeck HD, van de Leur E, Blaser J, Bender S, Gutgemann I, et al. Transforming growth factor beta 1 regulates tissue inhibitor of metalloproteinases-1 expression in differentiated human articular chondrocytes. Arthritis Rheum. 1994;37:395–405
  35. Qureshi HY, Sylvester J, El Mabrouk M, Zafarullah M. TGF-beta-induced expression of tissue inhibitor of metalloproteinases-3 gene in chondrocytes is mediated by extracellular signal-regulated kinase pathway and Sp1 transcription factor. J Cell Physiol. 2005;203:345–352
  36. Edwards DR, Murphy G, Reynolds JJ, Whitham SE, Docherty AJ, Angel P, et al. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J. 1987;6:1899–1904
  37. Overall CM, Wrana JL, Sodek J. Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta. J Biol Chem. 1989;264:1860–1869
  38. Canty EG, Kadler KE. Procollagen trafficking, processing and fibrillogenesis. J Cell Sci. 2005;118:1341–1353
  39. Lamande SR, Bateman JF. Procollagen folding and assembly: the role of endoplasmic reticulum enzymes and molecular chaperones. Semin Cell Dev Biol. 1999;10:455–464
  40. Prockop DJ, Sieron AL, Li SW. Procollagen N-proteinase and procollagen C-proteinase. Two unusual metalloproteinases that are essential for procollagen processing probably have important roles in development and cell signaling. Matrix Biol. 1998;16:399–408
  41. Myllyharju J, Kivirikko KI. Collagens and collagen-related diseases. Ann Med. 2001;33:7–21
  42. Kagan HM, Li W. Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell. J Cell Biochem. 2003;88:660–672
  43. Wildey GM, Billetz AC, Matyas JR, Adams ME, McDevitt CA. Absolute concentrations of mRNA for type I and type VI collagen in the canine meniscus in normal and ACL-deficient knee joints obtained by RNase protection assay. J Orthop Res. 2001;19:650–658
  44. Hellio Le Graverand MP, Reno C, Hart DA. Gene expression in menisci from the knees of skeletally immature and mature female rabbits. J Orthop Res. 1999;17:738–744
  45. Romanic AM, Adachi E, Kadler KE, Hojima Y, Prockop DJ. Copolymerization of pNcollagen III and collagen I. pNcollagen III decreases the rate of incorporation of collagen I into fibrils, the amount of collagen I incorporated, and the diameter of the fibrils formed. J Biol Chem. 1991;266:12703–12709
  46. Englund M, Roos EM, Lohmander LS. Impact of type of meniscal tear on radiographic and symptomatic knee osteoarthritis: a sixteen-year followup of meniscectomy with matched controls. Arthritis Rheum. 2003;48:2178–2187

PII: S1063-4584(10)00205-0

doi: 10.1016/j.joca.2010.05.017

Osteoarthritis and Cartilage
Volume 18, Issue 9 , Pages 1133-1143 , September 2010

Article Tools

* Image Usage & Resolution