Osteoarthritis and Cartilage
Volume 18, Issue 3 , Pages 279-288, March 2010

MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation – divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation

  • B.-C. Sondergaard

      Affiliations

    • Nordic Bioscience A/S, Herlev, Denmark
    • Corresponding Author InformationAddress correspondence and reprint requests to: Bodil-Cecilie Søndergaard, Nordic Bioscience, Herlev Hovedgade 207, DK-2730 Herlev, Denmark. Tel: 45-44-52-52-18; Fax: 45-44-52-52-51.
  • ,
  • N. Schultz

      Affiliations

    • Nordic Bioscience A/S, Herlev, Denmark
  • ,
  • S.H. Madsen

      Affiliations

    • Nordic Bioscience A/S, Herlev, Denmark
  • ,
  • A.-C. Bay-Jensen

      Affiliations

    • Nordic Bioscience A/S, Herlev, Denmark
  • ,
  • M. Kassem

      Affiliations

    • Department of Endocrinology, University of Southern Denmark, Odense, Denmark
  • ,
  • M.A. Karsdal

      Affiliations

    • Nordic Bioscience A/S, Herlev, Denmark

Received 4 June 2009; accepted 4 November 2009. published online 04 December 2009.

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PII: S1063-4584(09)00297-0

doi:10.1016/j.joca.2009.11.005

Osteoarthritis and Cartilage
Volume 18, Issue 3 , Pages 279-288, March 2010