Osteoarthritis and Cartilage
Volume 18, Issue 3 , Pages 354-357 , March 2010

Site specific osteoarthritis and the index to ring finger length ratio

  • B. Ferraro

      Affiliations

    • University of South Florida College of Public Health, Department of Epidemiology and Biostatistics, Tampa, FL 33612, USA
    • University of South Florida College of Medicine, Department of Molecular Medicine, Tampa, FL 33612, USA
    • ,
  • F.V. Wilder

      Affiliations

    • University of South Florida College of Public Health, Department of Epidemiology and Biostatistics, Tampa, FL 33612, USA
    • The Arthritis Research Institute of America, Clearwater, FL 33755, USA
    • Corresponding Author InformationAddress correspondence and reprint requests to: Frances V. Wilder, The Arthritis Research Institute of America, 300 South Duncan Avenue, Suite 188, Clearwater, FL 33755, USA. Tel: 1-727-46104054; Fax: 1-727-449-9227.
    • ,
  • P.E. Leaverton

      Affiliations

    • University of South Florida College of Public Health, Department of Epidemiology and Biostatistics, Tampa, FL 33612, USA
    • The Arthritis Research Institute of America, Clearwater, FL 33755, USA

Received 10 June 2009 ,Accepted 1 October 2009.

References 

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  2. Manning JT, Scutt D, Wilson J, Lewis-Jones DI. The ratio of 2nd to 4th digit length: a predictor of sperm numbers and concentrations of testosterone, luteinizing hormone and oestrogen. Hum Reprod. 1998;13(11):3000–3004
  3. Rizwan S, Manning JT, Brabin BJ. Maternal smoking during pregnancy and possible effects of in utero testosterone: evidence from the 2D:4D finger length ratio. Early Hum Dev. 2007;83(2):87–90
  4. Lutchmaya S, Baron-Cohen S, Raggatt P, Knickmeyer R, Manning JT. 2nd to 4th digit ratios, fetal testosterone and estradiol. Early Hum Dev. 2004;77(1):23–28
  5. Robert LM. Low digit ratio (2D:4D) is associated with delayed menarche. Am J Human Biol. 2008;20(4):487–489
  6. Brown WM, Hines M, Fane BA, Breedlove SM. Masculinized finger length patterns in human males and females with congenital adrenal hyperplasia. Horm Behav. 2002;42(4):380–386
  7. Fink B, Manning JT, Neave N. The 2nd–4th digit ratio (2D:4D) and neck circumference: implications for risk factors in coronary heart disease. Int J Obes (Lond). 2006;30(4):711–714
  8. Manning JT, Bundred PE. The ratio of 2nd to 4th digit length and age at first myocardial infarction in men: a link with testosterone?. Br J Cardiol. 2001;8:720–723
  9. Manning JT, Hill MR. Digit ratio (2D:4D) and sprinting speed in boys. Am J Human Biol. 2008;Epub ahead of print
  10. Manning JT, Morris L, Caswell N. Endurance running and digit ratio (2D:4D): implications for fetal testosterone effects on running speed and vascular health. Am J Human Biol. 2007;19(3):416–421
  11. Romano M, Leoni B, Saino N. Examination marks of male university students positively correlate with finger length ratios (2D:4D). Biol Psychol. 2006;71(2):175–182
  12. Fink B, Brookes H, Neave N, Manning J, Geary D. Second to fourth digit ratio and numerical competence in children. Brain Cogn. 2006;61(2):211–218
  13. Zhang W, Robertson J, Doherty S, Liu JJ, Maciewicz RA, Muir KR, et al. Index to ring finger length ratio and the risk of osteoarthritis. Arthritis Rheum. 2008;58(1):137–144
  14. Wilder FV, Barrett JP, Farina EJ. The association of radiographic foot osteoarthritis and radiographic osteoarthritis at other sites. Osteoarthr Cartil. 2005;13(3):211–215
  15. Rogers MW, Wilder FV. The association of BMI and knee pain among persons with radiographic knee osteoarthritis: a cross-sectional study. BMC Musculoskelet Disord. 2008;9(1):
  16. Wilder FV, Hall BJ, Barrett JP, Lemrow NB. History of acute knee injury and osteoarthritis of the knee: a prospective epidemiological assessment. The clearwater osteoarthritis study. Osteoarthr Cartil. 2002;10(8):611–616
  17. Wilder FV, Hall BJ, Barrett JP. Smoking and osteoarthritis: is there an association? The clearwater osteoarthritis study. Osteoarthr Cartil. 2003;11(1):29–35
  18. Kellgren JH, Lawrence JS. Atlas of Standard Radiographs: the Epidemiology of Chronic Rheumatism. Oxford: Blackwell Scientific; 1963;
  19. Robertson J, Zhang W, Liu JJ, Muir KR, Maciewicz RA, Doherty M. Radiographic assessment of the index to ring finger ratio (2D:4D) in adults. J Anat. 2008;212(1):42–48
  20. Talarovicová A, Krsková L, Blazeková J. Testosterone enhancement during pregnancy influences the 2D:4D ratio and open field motor activity of rat siblings in adulthood. Horm Behav. 2009;55(1):235–239
  21. Voracek M. Digit ratio (2D:4D) as a marker for mental disorders: low (masculinized) 2D:4D in autism-spectrum disorders, high (feminized) 2D:4D in schizophrenic-spectrum disorders. Behav Brain Sci. 2008;31:283–284
  22. Jurimae T, Voracek M, Jurimae J, Latt E, Haljaste K, Saar M, et al. Relationships between finger-length ratios, ghrelin, leptin, IGF axis, and sex steroids in young male and female swimmers. Eur J Appl Physiol. 2008;104(3):523–529
  23. Manning J, Callow M, Bundred P. Finger and toe ratios in humans and mice: implications for the aetiology of diseases influenced by HOX genes. Med Hypotheses. 2003;60(3):340–343
  24. Hanna F, Ebeling P, Wang Y, O'Sullivan R, Davis S, Wluka A, et al. Factors influencing longitudinal change in knee cartilage volume measured from magnetic resonance imaging in healthy men. Ann Rheum Dis. 2005;64(7):1038–1042

PII: S1063-4584(09)00292-1

doi: 10.1016/j.joca.2009.11.001

Osteoarthritis and Cartilage
Volume 18, Issue 3 , Pages 354-357 , March 2010

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