« Previous
Next »
Osteoarthritis and Cartilage
Volume 17, Issue 7
, Pages 896-905
, July 2009
Relative efficacies of omega-3 polyunsaturated fatty acids in reducing expression of key proteins in a model system for studying osteoarthritis
References
- . Cartilage catabolism in arthritis: factors that influence homeostasis. Rev Mol Med. 2001;3:1–20
- . The clinical management of rheumatoid arthritis and osteoarthritis: strategies for improving clinical effectiveness. British J Rheumatol. 1998;37:546–554
- . Mechanical factors in articular cartilage and their role in osteoarthritis. Osteoarthritis Disorders. American Acad Orthopedic Surgeons. 1995;147–171
- . Articular cartilage and changes in arthritis: matrix degradation. Arthritis Res. 2001;3:337–341
- . Differential expression of aggrecanase and matrix metalloproteinase activity in chondrocytes isolated from bovine and porcine articular cartilage. J Biol Chem. 1998;273:30576–30585
- . Roles of aggrecan: a large chondroitin sulphate proteoglycan, in cartilage structure and function. J Biochem (Tokyo). 1998;124:687–693
- Versican VI proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4. J Biol Chem. 2001;276:13372–13378
- Cloning and characterisation of ADAMTS11, an aggrecanase from the ADAMTS family. J Biol Chem. 1999;274:23443–23450
- . Generation and characterisation of aggrecanase. A soluble, cartilage-derived aggrecan-degrading activity. J Biol Chem. 1999;274:6594–6601
- Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Arthritis Rheum. 2004;50:2547–2558
- ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature. 2005;434:648–652
- Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature. 2005;434:644–648
- . The role of ADAMTS-4 (aggrecanase-1) and ADAMTS-5 (aggrecanase-2) in a model of cartilage degradation. Osteoarthritis Cartilage. 2001;9:539–552
- Proteolytic activities of human ADAMTS-5; comparative studies with ADAMTS-4. J Biol Chem. 2007;282:18294–18306
- Expression profiling of metalloproteinases and their inhibitors in cartilage. Arthritis Rheum. 2004;50:131–141
- . Metalloproteinases: their role in arthritis and potential as therapeutic targets. Expert Opin Ther Targets. 2005;7:19–34
- . Detection of stromelysin and collagenase in synovial fluid from patients with rheumatoid arthritis and post-traumatic knee injury. Arthritis Rheum. 1992;35:35–42
- . Matrix metalloproteinases and TIMPS: properties and implications for the rheumatic diseases. Mol Med Today. 1998;9:130–137
- . n-3 Polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale?. Nutri Res. 2001;21:309–341
- . Lipid Biochemistry. Fifth edn. Oxford: Blackwells Scientific; 2002;
- . Dietary omega-3 polyunsaturated fatty acids and inflammation. Lipid Technol. 2006;18:7–10
- . Resolvins, docosatrienes and neuroprotectins, novel omega-3-derived mediators and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis. Prostaglandins Other Lipid Mediat. 2004;73:155–172
- . Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr. 2002;21:495–505
- . Essential fatty acids in health and chronic disease. Am J Clin Nutr. 1999;70:560–569
- Cyclooxygenase in biology and disease. FASEB J. 1998;12:1063–1073
- . Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?. Biochem Pharmacol. 2001;62:1433–1438
- Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998;95:13313–13318
- . Cyclooxygenase 1 and 2. Annu Rev Pharmacol Toxicol. 1998;38:97–120
- . Cyclooxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy. Brit J Pharmacol. 1999;128:1121–1132
- . A lesson in unexpected problems. New Engl J Med. 2005;352:1131–1132
- . Problems with essential fatty acids: time for a new paradigm?. Prog Lipid Res. 2003;42:544–568
- . Recommendation for intake of polyunsaturated fatty acids in healthy adults. ISSFAL Newsl. 2004;11:12–25
- Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol. 2003;60:940–946
- . The rapid incorporation of phosphate in mitochondrial lipids. J Biol Chem. 1963;238:59–63
- . Fatty acid transport in articular cartilage. Arch Biochem Biophys. 2006;456:71–78
- Zainal Z. How can palm oil be modified to give improved dietary benefits?. Ph.D. thesis, University of Cardiff, UK, 2005.
- . Influence of interleukin-1 on the morphology and proteoglycan metabolism of cultured bovine articular chondrocytes. Connect Tissue Res. 1992;28:143–159
- . Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2. Rheumatology. 1999;38:779–788
- . Cytokines and their role in the pathophysiology of osteoarthritis. Frontiers Bioscience. 1999;4:694–703
- . n-3 fatty acids and cardiovascular disease: evidence explained and mechanisms explored. Clin Sci. 2004;107:1–11
- . Human dietary requirements. In: Gunstone FD, Harwood JL, Dijkstra AJ editor. The Lipid Handbook. Third edn. Boca Raton, Fl: Taylor and Francis; 2007;p. 703–710
- Photoprotective and anti-skin-aging effects of eicosapentaenoic acid in human skin in vitro. J Lipid Res. 2006;47:921–930
- The omega-3 fatty acid decosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKCE inhibition. Proc Natl Acad Sci U S A. 2006;103:15184–15189
- . Polyunsaturated fatty acid regulation of gene transcription: a molecular mechanism to improve the metabolic syndrome. J Nutr. 2001;131:1129–1132
- . The biochemistry of n-3 polyunsaturated fatty acids. J Biol Chem. 2002;277:8755–8758
- Hurst S. n-3 polyunsaturated fatty acid effects on inflammatory mediator activity and intracellular signalling pathways in chondrocyte metabolism. Ph.D. thesis, University of Cardiff, UK, 2004.
- Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants. Nature Biotechnol. 2004;22:739–745
- Stepwise metabolic engineering of economically significant amounts of very long chain polyunsaturated fatty acids in seeds of Brassica juncea. Nature Biotechnol. 2005;23:1013–1017
PII: S1063-4584(08)00382-8
doi: 10.1016/j.joca.2008.12.009
« Previous
Next »
Osteoarthritis and Cartilage
Volume 17, Issue 7
, Pages 896-905
, July 2009
